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KMID : 0380519970010020157
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Korean Journal of Veterinary Pathology
1997 Volume.1 No. 2 p.157 ~ p.160
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The Detection of Bovine Respiratory Syncytial Virus Using Immunohistochemistry and pathologic Findings
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Yoon Soon-Seek
Hwang Eui-Kyung
Moon Oun-Kyong
Bae You-Chan
Kim Jae-Hoon
Eom Hyun-Jong
Cho Jae-Jin
Jean Young-Hwa
Choi Sang-Ho
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Abstract
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Two 2 and 7 months-old holstin and one 3 months-old native Korean calf suffering from respiratory illness were submitted to the National Veterinary Research Institute for euthanasia and pathologic examination. At necropsy diffuse lobar pneumonia was present in apical cardiac and diaphragmatic lobes in all calves. Microscopically acute multifocal bronchiolitis and interstitial syncytial cell formation were frequently observed. in addition occlusion of bronchiolar lumen due to cellular proliferation and fibrosis accompanied by interlobular septal emphysema were also present. Immunohistochemically bovine respiratory syncytial virus antigen were positively identified in lung lesions including bronchial and bronchiolar epithelium alveolar macrophages and lymphocytes.
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KEYWORD
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BRSV, immunohistochemisty, pathology, calf
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